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Reasons for this phenomenon are not yet fully understood.

It can be difficult to clinically distinguish EVD from other infectious diseases such as malaria, typhoid fever and meningitis.

Samples collected from patients are an extreme biohazard risk; laboratory testing on non-inactivated samples should be conducted under maximum biological containment conditions.

All biological specimens should be packaged using the triple packaging system when transported nationally and internationally.

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There were more cases and deaths in this outbreak than all others combined.

The virus causing the 2014–2016 West African outbreak belongs to the Zaire ebolavirus species.

It is thought that fruit bats of the Pteropodidae family are natural Ebola virus hosts.

Within the genus Ebolavirus, five species have been identified: Zaire, Bundibugyo, Sudan, Reston and Taï Forest.

The first three, Bundibugyo ebolavirus, Zaire ebolavirus, and Sudan ebolavirus have been associated with large outbreaks in Africa.

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